Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 6/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801853 | 0.87 | ALDH1A1 (0.41) | HTR2AHTR2CHTR2BDRD2DRD3 | |
| SCHEMBL30801770 | 0.83 | TAAR1 (0.37) | HTR2AHTR2CHTR2BUSP30 | |
| SCHEMBL30801818 | 0.83 | GRM5 (0.43) | HTR2CHTR2BUSP30NOTUMDRD2 | |
| SCHEMBL23573969 | 0.83 | USP30 (0.47) | USP30NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL30986860 | 0.83 | USP30 (0.47) | USP30NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL23573970 | 0.83 | USP30 (0.47) | USP30NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL30801776 | 0.74 | XDH (0.40) | HTR2AHTR2CHTR2BUSP30SLC5A1 | |
| SCHEMBL30801864 | 0.71 | ALDH1A1 (0.51) | HTR2AHTR2CHTR2BDRD2DRD3 | |
| SCHEMBL23574112 | 0.70 | USP30 (0.43) | USP30NOTUMDRD2DRD3KCNH2 | |
| SCHEMBL23574114 | 0.70 | USP30 (0.43) | USP30NOTUMDRD2DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |