Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801818 | 0.87 | GRM5 (0.43) | HTR2CHTR2BUSP30 | |
| SCHEMBL30801853 | 0.85 | ALDH1A1 (0.41) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL30801845 | 0.83 | HTR2A (0.39) | HTR2AHTR2CHTR2BUSP30 | |
| SCHEMBL23574015 | 0.79 | USP30 (0.47) | DDB1CRBNUSP30USP7 | |
| SCHEMBL23574012 | 0.79 | USP30 (0.47) | DDB1CRBNUSP30USP7 | |
| SCHEMBL30801833 | 0.76 | F10 (0.40) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL30801761 | 0.75 | COMT (0.38) | TAAR1HTR2AHTR2CHTR2BUSP30 | |
| SCHEMBL30801775 | 0.74 | HTR1A (0.49) | TAAR1HTR2AHTR2CHTR2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL3609734 | 0.72 | TAAR1 (0.42) | TAAR1DDB1CRBNHTR2AHTR2C | |
| SCHEMBL30801891 | 0.72 | NPC1 (0.37) | TAAR1ALDH1A1SLC6A2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |