Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801805 | 1.00 | CRHBP (0.43) | CRHBPGFERCRHR2NOTUMGRM5 | |
| SCHEMBL30801719 | 0.89 | DRD2 (0.37) | NOTUMDRD2HTR2C | |
| SCHEMBL30801744 | 0.89 | NPC1 (0.38) | USP30PLATHTR2C | |
| SCHEMBL30801848 | 0.86 | USP30 (0.39) | USP30DRD2HTR2C | |
| SCHEMBL30801748 | 0.86 | USP30 (0.39) | USP30DRD2HTR2C | |
| SCHEMBL30801750 | 0.85 | PARP1 (0.39) | GRM5USP30PLAT | |
| SCHEMBL30801850 | 0.85 | USP30 (0.39) | GRM5HTR7USP30UCHL1HTR2C | |
| SCHEMBL30801776 | 0.83 | XDH (0.40) | GRM5USP30PLATHTR2C | |
| SCHEMBL23574140 | 0.80 | USP30 (0.49) | CRHBPGFERCRHR2USP30UCHL1 | |
| SCHEMBL23574046 | 0.80 | USP30 (0.49) | CRHBPGFERCRHR2USP30UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |