Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801719 | 0.89 | DRD2 (0.37) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL30801830 | 0.89 | CRHBP (0.43) | USP30PLATHTR2C | |
| SCHEMBL30801805 | 0.89 | CRHBP (0.43) | USP30PLATHTR2C | |
| SCHEMBL30801848 | 0.87 | USP30 (0.39) | USP30CPT1AHTR2CHTR2B | |
| SCHEMBL30801748 | 0.87 | USP30 (0.39) | USP30CPT1AHTR2CHTR2B | |
| SCHEMBL30801750 | 0.86 | PARP1 (0.39) | NPC1RAB9AUSP30PLATMEN1 | |
| SCHEMBL30801850 | 0.86 | USP30 (0.39) | NPC1RAB9AUSP30MEN1KMT2A | |
| SCHEMBL30801776 | 0.84 | XDH (0.40) | USP30PLATHTR2AHTR2CHTR2B | |
| SCHEMBL30801891 | 0.80 | NPC1 (0.37) | NPC1RAB9ATAAR1MEN1KMT2A | |
| SCHEMBL23574151 | 0.78 | USP30 (0.50) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |