Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801925 | 0.98 | DRD2 (0.49) | DRD2DRD3ALDH1A1HTR1AMEN1 | |
| SCHEMBL30802084 | 0.94 | KDM4E (0.49) | HTR1AMEN1KMT2AKDM4EPKM | |
| SCHEMBL29944565 | 0.89 | ALDH1A1 (0.57) | DRD2DRD3ALDH1A1HTR1AMEN1 | |
| SCHEMBL829637 | 0.89 | ALDH1A1 (0.57) | DRD2DRD3ALDH1A1HTR1AMEN1 | |
| SCHEMBL5475624 | 0.88 | ACHE (0.53) | ALDH1A1KDM4EPKM | |
| SCHEMBL12263981 | 0.88 | MAOB (0.57) | DRD2DRD3ALDH1A1HTR1AMEN1 | |
| SCHEMBL6953531 | 0.88 | ACHE (0.55) | ALDH1A1KDM4EPKM | |
| SCHEMBL29263692 | 0.88 | MAOB (0.57) | DRD2DRD3ALDH1A1HTR1AMEN1 | |
| SCHEMBL31596884 | 0.87 | GPR119 (0.53) | ALDH1A1KDM4EPKMHPGD | |
| SCHEMBL17844904 | 0.87 | DRD2 (0.56) | DRD2DRD3ALDH1A1HTR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054603-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |