Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21062750 | 0.86 | GAA (0.46) | GAAMAPK1HTTSMN1; SMN2NAAA | |
| SCHEMBL19692920 | 0.82 | GAA (0.41) | GAAMAPK1HTTSMN1; SMN2NAAA | |
| SCHEMBL953293 | 0.81 | GNAI3 (0.55) | GAAMAPK1HTTSMN1; SMN2NAAA | |
| SCHEMBL3332407 | 0.77 | NAAA (0.52) | GAAMAPK1HTTSMN1; SMN2NAAA | |
| SCHEMBL9218015 | 0.77 | NAAA (0.44) | GAAMAPK1HTTSMN1; SMN2NAAA | |
| SCHEMBL7747243 | 0.77 | NAAA (0.41) | GAAMAPK1HTTSMN1; SMN2NAAA | |
| SCHEMBL30059377 | 0.77 | SMN1; SMN2 (0.48) | GAAMAPK1HTTSMN1; SMN2NAAA | |
| Hydrochloric Acid SCHEMBL23850454 | 0.76 | NAAA (0.51) | GAAMAPK1HTTSMN1; SMN2NAAA | |
| SCHEMBL21856082 | 0.76 | EPHX1 (0.50) | GAAMAPK1HTTSMN1; SMN2NAAA | |
| SCHEMBL951710 | 0.75 | GAA (0.50) | GAAMAPK1HTTSMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054512-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |