Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CFTR | P13569 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30806660 | 0.90 | CFTR (0.52) | PKMALOX5PTGS2ALOX15CFTR | |
| SCHEMBL7969979 | 0.86 | MAPT (0.50) | MEN1KMT2ARAB9ACNR1ACHE | |
| SCHEMBL30806751 | 0.83 | ALOX5 (0.44) | PKMALOX5PTGS2ALOX15CFTR | |
| SCHEMBL15712417 | 0.79 | ALDH1A1 (0.52) | CFTRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL30806396 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AL3MBTL1CNR1 | |
| SCHEMBL31441369 | 0.79 | MEN1 (0.71) | ALOX5PTGS2ALOX15CFTRMEN1 | |
| SCHEMBL28987743 | 0.79 | MEN1 (0.71) | ALOX5PTGS2ALOX15CFTRMEN1 | |
| SCHEMBL30806419 | 0.78 | CFTR (0.60) | ALOX5PTGS2ALOX15CFTRMEN1 | |
| SCHEMBL30806936 | 0.78 | CFTR (0.65) | ALOX5PTGS2ALOX15CFTRMEN1 | |
| SCHEMBL2965240 | 0.78 | CFTR (0.50) | ALOX5PTGS2ALOX15CFTRPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561561-A2 | SUBSTITUTED 3,4-DIHYDROQUINOLINONE INHIBITORS OF TSHR | Septerna, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026076-A2 | SUBSTITUTED 3,4-DIHYDROQUINOLINONE INHIBITORS OF TSHR | SEPTERNA, INC. (US) | 2024-02-01 | — | — | WO | disclosed |