Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080764 | 0.87 | FAAH (0.50) | FAAHCXCR4ALDH1A1KDM4EMAPT | |
| SCHEMBL3080704 | 0.81 | FAAH (0.44) | FAAHCXCR4ALDH1A1KDM4EMAPT | |
| SCHEMBL21043995 | 0.81 | FAAH (0.44) | FAAHCXCR4ALDH1A1KDM4EDRD2 | |
| SCHEMBL30218427 | 0.81 | FAAH (0.44) | FAAHCXCR4ALDH1A1KDM4EDRD2 | |
| SCHEMBL939757 | 0.78 | CXCR4 (0.53) | CXCR4ALDH1A1KDM4EMAPTDRD2 | |
| SCHEMBL30218464 | 0.75 | FAAH (0.40) | FAAHCXCR4ALDH1A1KDM4EDRD2 | |
| SCHEMBL21044060 | 0.75 | FAAH (0.40) | FAAHCXCR4ALDH1A1KDM4EDRD2 | |
| SCHEMBL3088488 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1KDM4ETSHRMAPK1LMNA | |
| SCHEMBL24306636 | 0.73 | CXCR4 (0.47) | CXCR4ALDH1A1DRD2DRD3BCHE | |
| SCHEMBL3096649 | 0.70 | ALDH1A1 (0.66) | FAAHALDH1A1KDM4EMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234377-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | EVOTEC AG (DE) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234377-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | HPGDS, PTGDR, PTGIS | FAAH 24/4885CXCR4 1097/4885ALDH1A1 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.