Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | DCK | P27707 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13732234 | 0.86 | GBA1 (0.38) | GBA1LOXNR1H2NR1H3EPAS1 | |
| SCHEMBL13731094 | 0.80 | LOX (0.39) | GBA1LOXKAT6ANR1H2NR1H3 | |
| SCHEMBL13730672 | 0.77 | EPAS1 (0.38) | GBA1LOXKAT6ANR1H2NR1H3 | |
| SCHEMBL17530475 | 0.77 | LOX (0.35) | GBA1LOXNR1H2NR1H3EPAS1 | |
| SCHEMBL13730404 | 0.76 | KDM4E (0.44) | GBA1KAT6A | |
| SCHEMBL13730289 | 0.75 | GBA1 (0.35) | GBA1LOXKAT6ANR1H2NR1H3 | |
| SCHEMBL13732231 | 0.75 | ALDH1A1 (0.39) | GBA1LOXKAT6ADCK | |
| SCHEMBL13731063 | 0.75 | MAPT (0.47) | TSHR | |
| SCHEMBL13730661 | 0.74 | ADRB2 (0.40) | GBA1KAT6ADCK | |
| Mesdopetam SCHEMBL13732678 | 0.74 | KAT6A (0.40) | GBA1KAT6ATSHRDCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577201-A1 | MESDOPETAM COMPOSITIONS | Alkem Laboratories Limited (IN) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024042540-A1 | MESDOPETAM COMPOSITIONS | ALKEM LABORATORIES LIMITED (IN) | 2024-02-29 | — | — | WO | disclosed |