Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.53 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 7/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 6/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.41 |
| ▸ | PLK4 | O00444 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | MARK3 | P27448 | 2/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | STK3 | Q13188 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18312205 | 1.00 | IKBKB (0.53) | IKBKBKITCDC7LIMK1DBF4 | |
| SCHEMBL14871305 | 0.79 | KIT (0.44) | IKBKBKITCDC7LIMK1DBF4 | |
| SCHEMBL4798991 | 0.76 | KMT2A (0.50) | IKBKBKITDYRK1ANPC1ALDH1A1 | |
| SCHEMBL21536748 | 0.76 | SMN1; SMN2 (0.39) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL21348213 | 0.73 | KIT (0.40) | KIT | |
| SCHEMBL19261300 | 0.73 | KIT (0.40) | KIT | |
| SCHEMBL4799418 | 0.73 | ALDH1A1 (0.42) | KITALDH1A1CSNK2A1STK17A | |
| SCHEMBL16190265 | 0.73 | KIT (0.40) | KITL3MBTL1 | |
| SCHEMBL3547186 | 0.71 | NOS1 (0.38) | KITPI4KAPI4KBNOS1 | |
| SCHEMBL29565259 | 0.71 | NCF1 (0.38) | KITCDK2KDM4EPI4KAPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | claimed |
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |