Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808174 | 0.86 | CYP1A2 (0.50) | ALDH1A1MEN1KMT2APIM1PIM2 | |
| SCHEMBL30808144 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2APIM1PIM2 | |
| SCHEMBL30808196 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2APIM1PIM2 | |
| SCHEMBL30808205 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2APIM1PIM2 | |
| SCHEMBL30808177 | 0.77 | MET (0.47) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL18739631 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL18739629 | 0.77 | MET (0.47) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL31326611 | 0.73 | HRH4 (0.48) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL31353546 | 0.73 | KMT2A (0.44) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL30762651 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026419-A1 | QUINOXALINE DERIVATIVES AS PIK3 ALPHA MODULATORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |