Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18739629 | 1.00 | MET (0.47) | METSMN1; SMN2KMT2AMEN1CRHBP | |
| SCHEMBL18739631 | 0.89 | ALDH1A1 (0.43) | METSMN1; SMN2KMT2AMEN1CRHBP | |
| SCHEMBL30808197 | 0.87 | MET (0.50) | METSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL30808192 | 0.87 | MET (0.50) | METSMN1; SMN2CRHBPCRHR2KDM4E | |
| SCHEMBL30808201 | 0.86 | MET (0.49) | METSMN1; SMN2CRHBPCRHR2NPC1 | |
| SCHEMBL18739760 | 0.86 | KMT2A (0.46) | SMN1; SMN2KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL30808213 | 0.84 | MET (0.46) | METSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL18739601 | 0.81 | PIK3CA (0.45) | SMN1; SMN2ALDH1A1KDM4EHPGDPIK3CD | |
| SCHEMBL30808159 | 0.81 | MET (0.49) | MET | |
| SCHEMBL30808207 | 0.80 | MET (0.44) | METSMN1; SMN2KMT2ACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026419-A1 | QUINOXALINE DERIVATIVES AS PIK3 ALPHA MODULATORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |