Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808205 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1PRKDCNUDT1 | |
| SCHEMBL30808188 | 0.88 | CYP1A2 (0.47) | ALDH1A1KMT2AMEN1PRKDCNUDT1 | |
| SCHEMBL30808156 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1NUDT1PIM1 | |
| SCHEMBL30808207 | 0.79 | MET (0.44) | ALDH1A1KMT2ACRHBPCRHR2GAA | |
| SCHEMBL30808147 | 0.78 | PIK3CB (0.33) | ALDH1A1KMT2AMEN1PIM1PIM2 | |
| SCHEMBL30808144 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1PRKDCNUDT1 | |
| SCHEMBL30762612 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1GAAKDM4E | |
| SCHEMBL30808202 | 0.73 | FFAR2 (0.35) | — | |
| SCHEMBL31284292 | 0.73 | MEN1 (0.36) | KMT2AMEN1PRKDCATMPIK3CA | |
| SCHEMBL31183501 | 0.72 | PIK3CA (0.51) | PRKDCPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026419-A1 | QUINOXALINE DERIVATIVES AS PIK3 ALPHA MODULATORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |