Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MET | P08581 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808193 | 0.84 | MAPT (0.57) | MAPTLMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL30808197 | 0.80 | MET (0.50) | MAPTSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL30808192 | 0.80 | MET (0.50) | SMN1; SMN2METKDM4EGAAHTR3A | |
| SCHEMBL30808201 | 0.79 | MET (0.49) | MAPTLMNASMN1; SMN2NPSR1MET | |
| SCHEMBL30808177 | 0.77 | MET (0.47) | MAPTLMNASMN1; SMN2METALDH1A1 | |
| SCHEMBL18739629 | 0.77 | MET (0.47) | MAPTLMNASMN1; SMN2METALDH1A1 | |
| SCHEMBL7697304 | 0.75 | MAPT (0.77) | MAPTLMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL30808158 | 0.74 | AKT1 (0.56) | MAPTLMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL16071189 | 0.71 | SMN1; SMN2 (0.57) | MAPTLMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL30808150 | 0.70 | MET (0.41) | MAPTLMNASMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026419-A1 | QUINOXALINE DERIVATIVES AS PIK3 ALPHA MODULATORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |