Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808192 | 0.97 | MET (0.50) | METHRH4HCRTR2HCRTR1HTR3A | |
| SCHEMBL30808201 | 0.96 | MET (0.49) | METHRH4HCRTR2HCRTR1HTR3A | |
| SCHEMBL30808177 | 0.87 | MET (0.47) | METKDM4EGAATDP1NPC1 | |
| SCHEMBL18739629 | 0.87 | MET (0.47) | METKDM4EGAATDP1NPC1 | |
| SCHEMBL30808150 | 0.85 | MET (0.41) | METHRH4HCRTR2HCRTR1HTR3A | |
| SCHEMBL30808190 | 0.80 | MAPT (0.60) | METHRH4HTR3AKDM4EGAA | |
| SCHEMBL30808227 | 0.78 | MET (0.46) | METHRH4HTR3A | |
| SCHEMBL18739631 | 0.76 | ALDH1A1 (0.43) | METHRH4KDM4EGAATDP1 | |
| SCHEMBL30808172 | 0.74 | MET (0.46) | METL3MBTL1KDM4EGAATDP1 | |
| SCHEMBL30808162 | 0.74 | SMN1; SMN2 (0.48) | METL3MBTL1KDM4EGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026419-A1 | QUINOXALINE DERIVATIVES AS PIK3 ALPHA MODULATORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |