Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808192 | 0.99 | MET (0.50) | METL3MBTL1KDM4EGAATDP1 | |
| SCHEMBL30808197 | 0.96 | MET (0.50) | METL3MBTL1KDM4EGAATDP1 | |
| SCHEMBL30808150 | 0.87 | MET (0.41) | METL3MBTL1KDM4EGAATDP1 | |
| SCHEMBL18739629 | 0.86 | MET (0.47) | METKDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL30808177 | 0.86 | MET (0.47) | METKDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL30808190 | 0.79 | MAPT (0.60) | METKDM4EGAAHRH4SMN1; SMN2 | |
| SCHEMBL30808172 | 0.79 | MET (0.46) | METL3MBTL1KDM4EGAATDP1 | |
| SCHEMBL30808162 | 0.79 | SMN1; SMN2 (0.48) | METL3MBTL1KDM4EGAATDP1 | |
| SCHEMBL28998457 | 0.76 | HPGD (0.42) | KDM4EGAASMN1; SMN2NPSR1TSHR | |
| SCHEMBL30808174 | 0.75 | CYP1A2 (0.50) | KDM4ETDP1HRH4SMN1; SMN2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026419-A1 | QUINOXALINE DERIVATIVES AS PIK3 ALPHA MODULATORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |