Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543361 | 0.91 | GPR119 (0.53) | GPR119USP30MAPTTP53NR1H2 | |
| SCHEMBL30812216 | 0.80 | GPR119 (0.53) | GPR119USP30MAPTNR1H2NR1H3 | |
| SCHEMBL5544207 | 0.79 | NPY2R (0.42) | GPR119HRH3MAPTPDE4B | |
| SCHEMBL30812268 | 0.76 | GPR119 (0.45) | GPR119USP30MAPTTP53NR1H2 | |
| SCHEMBL15442067 | 0.75 | GPR119 (0.64) | GPR119MAPT | |
| SCHEMBL25931020 | 0.74 | GPR119 (0.44) | GPR119USP30TP53PDE4B | |
| SCHEMBL25931356 | 0.74 | GPR119 (0.44) | GPR119USP30TP53PDE4B | |
| SCHEMBL30493371 | 0.74 | GPR119 (0.44) | GPR119USP30TP53PDE4B | |
| SCHEMBL25931015 | 0.74 | GPR119 (0.44) | GPR119USP30TP53PDE4B | |
| SCHEMBL28795341 | 0.70 | ALDH1A1 (0.45) | GPR119MAPTPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054956-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |