Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30813244 | 0.96 | LOX (0.41) | LOXLOXL3LOXL2MMP2MMP3 | |
| SCHEMBL30813097 | 0.84 | POLB (0.49) | PREP | |
| SCHEMBL30813118 | 0.82 | ALDH1A1 (0.45) | — | |
| SCHEMBL30813065 | 0.82 | LOXL2 (0.44) | LOXLOXL2 | |
| SCHEMBL30813139 | 0.82 | LOX (0.44) | LOXLOXL2GRM5PREP | |
| SCHEMBL30813108 | 0.81 | GRM5 (0.53) | GRM5 | |
| SCHEMBL30813113 | 0.81 | GRM5 (0.40) | MMP2MMP3MMP9MMP13GRM5 | |
| SCHEMBL30813188 | 0.81 | FAAH (0.39) | MMP2MMP3MMP9MMP13 | |
| SCHEMBL30813224 | 0.80 | LMNA (0.45) | — | |
| SCHEMBL30813047 | 0.79 | PREP (0.50) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3455224-B1 | SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF | BAYER AG (DE) | 2024-03-27 | — | — | EP | disclosed |