Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078658 | 0.98 | CALM1 (0.39) | SIGMAR1CALM1EPHX1TSHRIDO1 | |
| SCHEMBL23286140 | 0.87 | CALM1 (0.43) | SIGMAR1CALM1EPHX1TSHRIDO1 | |
| SCHEMBL3081821 | 0.77 | CALM1 (0.35) | SIGMAR1CALM1EPHX1TSHRIDO1 | |
| SCHEMBL30237031 | 0.71 | SIGMAR1 (0.44) | SIGMAR1IDO1SLC6A3 | |
| SCHEMBL4423634 | 0.70 | — | — | |
| Cyclooctane SCHEMBL18187569 | 0.68 | SIGMAR1 (0.58) | SIGMAR1LOXL2ALDH1A1SLC6A3 | |
| Ethylbenzene SCHEMBL7902673 | 0.64 | TP53 (0.82) | SIGMAR1CALM1TSHRIDO1TP53 | |
| Ethylbenzene SCHEMBL28826931 | 0.64 | TP53 (0.82) | SIGMAR1CALM1TSHRIDO1TP53 | |
| Ethylbenzene SCHEMBL11052893 | 0.64 | TP53 (0.82) | SIGMAR1CALM1TSHRIDO1TP53 | |
| Benzyl Alcohol SCHEMBL11329661 | 0.64 | TSHR (0.82) | SIGMAR1CALM1TSHRIDO1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240076305-A1 | Phosphonium Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2024-03-07 | — | — | US | disclosed |
| US-11618761-B2 | Phosphonium ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2023-04-04 | — | — | US | disclosed |
| EP-4054336-A1 | PHOSPHONIUM ION CHANNEL BLOCKERS AND METHODS FOR USE | Nocion Therapeutics, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| US-20210130380-A1 | PHOSPHONIUM ION CHANNEL BLOCKERS AND METHODS FOR USE | Nocion Therapeutics, Inc. | 2021-05-06 | — | — | US | disclosed |
| US-7833331-B2 | Non-toxic corrosion-protection pigments based on cobalt | UNIVERSITY OF DAYTON (US) | 2010-11-16 | — | — | US | disclosed |
| US-7789958-B2 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090163628-A1 | NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT | STURGILL JEFFREY ALLEN | 2009-06-25 | — | — | US | disclosed |
| US-7537663-B2 | Corrosion-inhibiting coating | UNIVERSITY OF DAYTON (US) | 2009-05-26 | — | — | US | disclosed |
| US-7422793-B2 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | UNIVERSITY OF DAYTON (US) | 2008-09-09 | — | — | US | disclosed |
| US-7407711-B2 | Non-toxic corrosion-protection conversion coats based on rare earth elements | UNIVERSITY OF DAYTON (US) | 2008-08-05 | — | — | US | disclosed |
| US-20040020568-A1 | Non-toxic corrosion-protection conversion coats based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-02-05 | — | — | US | disclosed |
| WO-2004009869-A2 | CORROSION-INHIBITING COATING FOR METAL SURFACES | UNIVERSITY OF DAYTON (US) | 2004-01-29 | — | — | WO | disclosed |
| US-20040016363-A1 | CORROSION-INHIBITING COATING | VENTURE LENDING & LEASING, IV, INC. | 2004-01-29 | — | — | US | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130380-A1 | PHOSPHONIUM ION CHANNEL BLOCKERS AND METHODS FOR USE | TRPV1, TRPV5, TRPA1 | SIGMAR1 916/4885CALM1 698/4885EPHX1 824/4885 |
| US-11618761-B2 | Phosphonium ion channel blockers and methods for use | TRPV1, TRPV5, TRPA1 | SIGMAR1 916/4885CALM1 698/4885EPHX1 824/4885 |
| US-20240076305-A1 | Phosphonium Ion Channel Blockers and Methods for Use | TRPV1, TRPV5, TRPA1 | SIGMAR1 916/4885CALM1 698/4885EPHX1 824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.