SCHEMBL30817311

SCHEMBL30817311

NC(N)=NCCC[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RARS1 P54136 1/20 1.00
SARS1 P49591 1/20 0.76
MARS1 P56192 1/20 0.75
LARS1 Q9P2J5 2/20 0.73
TARS1 P26639 2/20 0.71
IARS1 P41252 1/20 0.68
HARS1 P12081 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390953 0.89 SARS1 (0.81) RARS1SARS1MARS1LARS1TARS1
SCHEMBL13773212 0.89 MARS1 (0.82) RARS1SARS1MARS1LARS1TARS1
SCHEMBL13773214 0.89 MARS1 (0.82) RARS1SARS1MARS1LARS1TARS1
SCHEMBL4253015 0.89 SARS1 (0.81) RARS1SARS1MARS1LARS1TARS1
SCHEMBL13773213 0.89 MARS1 (0.82) RARS1SARS1MARS1LARS1TARS1
SCHEMBL5063189 0.89 SARS1 (0.82) RARS1SARS1MARS1LARS1TARS1
SCHEMBL5063184 0.89 SARS1 (0.82) RARS1SARS1MARS1LARS1TARS1
SCHEMBL3187665 0.88 SARS1 (0.87) RARS1SARS1MARS1LARS1TARS1
SCHEMBL21068060 0.88 SARS1 (0.87) RARS1SARS1MARS1LARS1TARS1
SCHEMBL3187637 0.88 SARS1 (0.87) RARS1SARS1MARS1LARS1TARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117503791-B Application of Arg-AMS compound in preparation of anti-PRRSV (porcine reproductive and respiratory syndrome virus) drug 华南农业大学 2024-11-19 CN claimed
CN-117503791-A Application of Arg-AMS compound in preparation of anti-PRRSV (porcine reproductive and respiratory syndrome virus) drug 华南农业大学 2024-02-06 CN claimed
CN-117503791-B Application of Arg-AMS compound in preparation of anti-PRRSV (porcine reproductive and respiratory syndrome virus) drug 华南农业大学 2024-11-19 CN disclosed
CN-117503791-B Application of Arg-AMS compound in preparation of anti-PRRSV (porcine reproductive and respiratory syndrome virus) drug 华南农业大学 2024-11-19 CN disclosed
CN-117503791-B Application of Arg-AMS compound in preparation of anti-PRRSV (porcine reproductive and respiratory syndrome virus) drug 华南农业大学 2024-11-19 CN disclosed
CN-117503791-A Application of Arg-AMS compound in preparation of anti-PRRSV (porcine reproductive and respiratory syndrome virus) drug 华南农业大学 2024-02-06 CN disclosed
CN-117503791-A Application of Arg-AMS compound in preparation of anti-PRRSV (porcine reproductive and respiratory syndrome virus) drug 华南农业大学 2024-02-06 CN disclosed
CN-117503791-A Application of Arg-AMS compound in preparation of anti-PRRSV (porcine reproductive and respiratory syndrome virus) drug 华南农业大学 2024-02-06 CN disclosed