Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668265 | 0.76 | KDM1A (0.48) | MEN1RAB9AKMT2AHTR2AHTR2C | |
| SCHEMBL26269465 | 0.69 | LMNA (0.46) | KMT2AACHEHRH3 | |
| SCHEMBL29168250 | 0.69 | — | — | |
| SCHEMBL30818100 | 0.66 | CYP4F2 (0.31) | — | |
| SCHEMBL24468257 | 0.66 | CXCR4 (0.39) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL15120060 | 0.65 | GRN (0.33) | — | |
| SCHEMBL23501941 | 0.62 | HRH3 (0.33) | MEN1KMT2AOPRL1HRH3BACE1 | |
| SCHEMBL30703236 | 0.61 | KEAP1 (0.37) | RAB9A | |
| SCHEMBL24258306 | 0.61 | MEN1 (0.53) | MEN1RAB9AKMT2AACHEHRH3 | |
| SCHEMBL662711 | 0.61 | MAOA (0.57) | MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |