SCHEMBL30818693

SCHEMBL30818693

Fc1cccc(N2CCOCC2)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.51
HTT P42858 1/20 0.47
POLB P06746 1/20 0.46
CNR2 P34972 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
PIK3CA P42336 2/20 0.44
PIK3CD O00329 1/20 0.44
NPSR1 Q6W5P4 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
PIM1 P11309 1/20 0.43
DRD2 P14416 2/20 0.43
DRD3 P35462 2/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
ALOX5 P09917 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2371248 1.00 GAA (0.51) GAAHTTPOLBCNR2SMN1; SMN2
SCHEMBL6843345 0.86 GAA (0.59) GAAHTTPOLBSMN1; SMN2PIK3CA
Phenylboronic Acid SCHEMBL3453507 0.85 GAA (0.44) GAAHTTPOLBCNR2SMN1; SMN2
SCHEMBL14897578 0.82 ALOX5 (0.46) SMN1; SMN2MAPTTSHRDRD2DRD3
SCHEMBL14896676 0.82 ALOX5 (0.46) GAASMN1; SMN2MAPTDRD2DRD3
SCHEMBL31195791 0.81 HSD17B14 (0.47) GAAPOLBSMN1; SMN2MAPTTSHR
SCHEMBL22334883 0.79 GAA (0.53) GAAHTTPOLBSMN1; SMN2PIK3CA
SCHEMBL4945956 0.78 GAA (0.59) GAAHTTPOLBCNR2SMN1; SMN2
SCHEMBL17787692 0.78 GAA (0.51) GAAHTTPOLBSMN1; SMN2PIK3CA
SCHEMBL12654053 0.78 HTR3E (0.64) GAAHTTPOLBSMN1; SMN2PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709373-A2 HETEROCYCLIC COMPOUNDS FOR IMAGING AGGREGATED TAU IN TAUOPATHIES University of Pittsburgh - Of the Commonwealth System of Higher Education (US) 2026-03-18 EP disclosed
EP-4587435-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS Cullgen (Shanghai), Inc. (CN) 2025-07-23 EP disclosed
WO-2024233875-A2 HETEROCYCLIC COMPOUNDS FOR IMAGING AGGREGATED TAU IN TAUOPATHIES UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2024-11-14 WO disclosed
WO-2024056077-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS CULLGEN (SHANGHAI) , INC. (CN) 2024-03-21 WO disclosed