SCHEMBL30818754

SCHEMBL30818754

Oc1ccc2c(c1)CCC=C2c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
CYP2C19 P33261 1/20 0.50
PTGS2 P35354 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HIF1A Q16665 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
GSTP1 P09211 2/20 0.47
ESR1 P03372 3/20 0.47
MAOB P27338 6/20 0.46
MAOA P21397 3/20 0.46
GAA P10253 3/20 0.45
MGAM O43451 2/20 0.45
SI P14410 2/20 0.45
MGAM2 Q2M2H8 2/20 0.45
MCL1 Q07820 1/20 0.43
PTPN1 P18031 1/20 0.42
CYP17A1 P05093 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18815890 0.93 MAOA (0.52) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL23740183 0.87 MAOB (0.56) GSTP1MAOBMAOAKDM4EALDH1A1
SCHEMBL23297253 0.87 MPO (0.50) GSTP1ESR1MAOBMAOAGAA
SCHEMBL20234894 0.86 MAOB (0.50) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL29966533 0.85 MAOB (0.53) GSTP1MAOBMAOAMCL1
SCHEMBL20231841 0.84 MAOB (0.56) GSTP1MAOBMAOACYP11B2
SCHEMBL22283927 0.83 RXRA (0.56) GSTP1MAOBMAOA
SCHEMBL20211880 0.82 MAOB (0.49) PTGS1PTGS2GSTP1MAOBMAOA
SCHEMBL20234621 0.82 CYP3A4 (0.53) GSTP1MAOBMAOAMCL1CYP17A1
SCHEMBL29683716 0.82 MAOB (0.49) PTGS1PTGS2GSTP1MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587435-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS Cullgen (Shanghai), Inc. (CN) 2025-07-23 EP disclosed
WO-2024056077-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS CULLGEN (SHANGHAI) , INC. (CN) 2024-03-21 WO disclosed