Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.53 |
| ▸ | MAOA | P21397 | 8/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23740183 | 0.92 | MAOB (0.56) | MAOBMAOAHRH3GSTP1TOP1 | |
| SCHEMBL18815890 | 0.90 | MAOA (0.52) | MAOBMAOAHRH3GSTP1TOP1 | |
| SCHEMBL28445218 | 0.87 | MAOB (0.51) | MAOBMAOAHRH3GSTP1TOP1 | |
| SCHEMBL23297253 | 0.87 | MPO (0.50) | MAOBMAOAHRH3GSTP1 | |
| SCHEMBL20231841 | 0.86 | MAOB (0.56) | MAOBMAOAHRH3GSTP1AR | |
| SCHEMBL21982918 | 0.86 | MAOB (0.51) | MAOBMAOAHRH3GSTP1TOP1 | |
| SCHEMBL30818754 | 0.85 | LMNA (0.50) | MAOBMAOAGSTP1MCL1 | |
| SCHEMBL22283927 | 0.85 | RXRA (0.56) | MAOBMAOAGSTP1 | |
| SCHEMBL20211880 | 0.84 | MAOB (0.49) | MAOBMAOAHRH3GSTP1TOP1 | |
| SCHEMBL20234621 | 0.84 | CYP3A4 (0.53) | MAOBMAOAHRH3GSTP1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917280-B | Tetrahydronaphthalene compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-20260098027-A1 | PHARMACEUTICALLY ACCEPTABLE SALT AND CRYSTAL FORM OF TETRAHYDRONAPHTHALENE DERIVATIVE, AND PREPARATION METHOD | JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) | 2026-04-09 | — | — | US | disclosed |
| EP-4596538-A1 | PHARMACEUTICALLY ACCEPTABLE SALT AND CRYSTAL FORM OF TETRAHYDRONAPHTHALENE DERIVATIVE, AND PREPARATION METHOD | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2025-08-06 | — | — | EP | disclosed |
| CN-120035586-A | Pharmaceutically acceptable salts and crystal forms of tetrahydronaphthalene derivatives and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-20250099596-A1 | TETRAHYDRONAPHTHALENE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2025-03-27 | — | — | US | disclosed |
| EP-4317146-A1 | TETRAHYDRONAPHTHALENE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2024-02-07 | — | — | EP | disclosed |
| CN-116917280-A | Tetrahydronaphthalene compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| WO-2022206737-A1 | TETRAHYDRONAPHTHALENE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2022-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260098027-A1 | PHARMACEUTICALLY ACCEPTABLE SALT AND CRYSTAL FORM OF TETRAHYDRONAPHTHALENE DERIVATIVE, AND PREPARATION METHOD | MDH2, MDH1, GOT1 | MAOB 4519/4885MAOA 4697/4885HRH3 2662/4885 |
| US-20250099596-A1 | TETRAHYDRONAPHTHALENE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | CYP51A1, CYP46A1, HSD17B11 | MAOB 1422/4885MAOA 1529/4885HRH3 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.