Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLK1 | O15075 | 1/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCND2 | P30279 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177900 | 1.00 | DCLK1 (0.39) | DCLK1MAPK7LRRK2ACVR1CCNB2 | |
| SCHEMBL21187336 | 1.00 | DCLK1 (0.39) | DCLK1MAPK7LRRK2ACVR1CCNB2 | |
| SCHEMBL21187331 | 0.86 | MEN1 (0.38) | DCLK1MAPK7LRRK2ALDH1A1IRAK4 | |
| SCHEMBL30823285 | 0.86 | MEN1 (0.38) | DCLK1MAPK7LRRK2ALDH1A1IRAK4 | |
| SCHEMBL21178069 | 0.86 | MEN1 (0.38) | DCLK1MAPK7LRRK2ALDH1A1IRAK4 | |
| SCHEMBL21177939 | 0.83 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1MAPK1SYK | |
| SCHEMBL30823280 | 0.83 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1MAPK1SYK | |
| SCHEMBL21187335 | 0.83 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1MAPK1SYK | |
| SCHEMBL21187359 | 0.82 | ALDH1A1 (0.40) | DCLK1MAPK7LRRK2L3MBTL1ALDH1A1 | |
| SCHEMBL28471532 | 0.82 | ALDH1A1 (0.40) | DCLK1MAPK7LRRK2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757876-B | DNA-PK inhibitors | 沃泰克斯药物股份有限公司 | 2024-03-22 | — | — | CN | disclosed |