Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27171254 | 1.00 | ALDH1A1 (0.45) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 | |
| SCHEMBL27171252 | 0.79 | NTRK1 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 | |
| SCHEMBL27171246 | 0.78 | EGFR (0.45) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 | |
| SCHEMBL27171253 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 | |
| SCHEMBL27171249 | 0.76 | PTPN1 (0.47) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 | |
| SCHEMBL30823700 | 0.76 | PTPN1 (0.47) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 | |
| SCHEMBL26341725 | 0.71 | LMNA (0.67) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 | |
| SCHEMBL30823693 | 0.71 | LMNA (0.43) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 | |
| SCHEMBL26352669 | 0.67 | LMNA (0.57) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 | |
| SCHEMBL27172726 | 0.67 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTSMN1; SMN2CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617771-B2 | Diphenylpyrazole compound, and preparation method therefor and application thereof | NORTHWEST A&F UNIVERSITY (CN) | 2026-05-05 | — | — | US | disclosed |
| US-20240083871-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | NORTHWEST A&F UNIVERSITY (CN) | 2024-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617771-B2 | Diphenylpyrazole compound, and preparation method therefor and application thereof | GSTP1, GSTO1, GSTA1 | ALDH1A1 334/4885LMNA 4677/4885HTT 4506/4885 |
| US-20240083871-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | GSTP1, CYP4F11, GSTA1 | ALDH1A1 467/4885LMNA 4766/4885HTT 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.