Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL11403488 | 0.94 | ALDH1A1 (0.88) | ALDH1A1RAB9ANPC1LMNATSHR | |
| SCHEMBL4198688 | 0.92 | ALDH1A1 (0.69) | ALDH1A1RAB9ANPC1EPHX1NAAA | |
| SCHEMBL9581057 | 0.90 | ALDH1A1 (0.64) | ALDH1A1RAB9ANPC1IDO1AGXT | |
| SCHEMBL14063398 | 0.90 | ALDH1A1 (0.64) | ALDH1A1RAB9ANPC1IDO1AGXT | |
| SCHEMBL14063393 | 0.90 | ALDH1A1 (0.64) | ALDH1A1RAB9ANPC1IDO1AGXT | |
| SCHEMBL3082525 | 0.89 | RAB9A (0.62) | ALDH1A1RAB9ANPC1GAAMAPT | |
| E1501 SCHEMBL28201296 | 0.88 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1LMNATSHR | |
| E1501 SCHEMBL901210 | 0.88 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1LMNATSHR | |
| E1501 SCHEMBL14031569 | 0.88 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1LMNATSHR | |
| E1501 SCHEMBL43745 | 0.88 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083933-A1 | NEUTRAL BRUSHES WITH TUNABLE POLARITY FOR SELF-ASSEMBLY OF BLOCK COPOLYMERS WITH POLY(STYRENE) AND POLY(METHYL METHACRYLATE) CONTAINING SEGMENTS | MERCK PATENT GMBH (DE) | 2023-05-19 | — | — | WO | disclosed |
| US-20130338363-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | NIPPON SHOKUBAI CO., LTD. (JP) | 2013-12-19 | — | — | US | disclosed |
| US-8541532-B2 | Silane compound, production method thereof, and resin composition containing silane compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| EP-2180019-B1 | Resin composition, method of its composition, and cured formulation | NIPPON CATALYTIC CHEM IND (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20100317774-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | NIPPON SHOKUBAI CO., LTD (JP) | 2010-12-16 | — | — | US | disclosed |
| US-7825149-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2010-11-02 | — | — | US | disclosed |
| US-7723407-B2 | mixing a phenolic compound containing the inorganic microfine particle(SiO2) and a compound containing at least one of the glycidyl group and/or an epoxy group containing the inorganic microfine particle; fireproofing; good mechanical properties; heat resistance; automobiles, construction, electronics | NIPPON SHOKUBAI CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| EP-2180019-A1 | Resin composition, method of its composition, and cured formulation | Nippon Shokubai Co., Ltd. (JP) | 2010-04-28 | — | — | EP | disclosed |
| US-20090312326-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2009-12-17 | — | — | US | disclosed |
| US-7592362-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-09-22 | — | — | US | disclosed |
| US-7547718-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-16 | — | — | US | disclosed |
| US-7544706-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-09 | — | — | US | disclosed |
| US-20090010603-A1 | Resin Composition for Optical Packaging Material and Process for Preparing the Same, and Optical Packaging Material, Optical Packaging Component, and Optical Module | NIPPON SHOKUBAI CO., LTD. (JP) | 2009-01-08 | — | — | US | disclosed |
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-29 | — | — | US | disclosed |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-22 | — | — | US | disclosed |
| CN-101094827-A | Benzene compound having two or more substituents | SANKYO CO (JP) | 2007-12-26 | — | — | CN | disclosed |
| WO-2007083207-A1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LIMITED (GB) | 2007-07-26 | — | — | WO | disclosed |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | PFIZER INC. (US) | 2007-07-19 | — | — | US | disclosed |
| EP-1626065-A1 | Resin composition, method of its composition, and cured formulation | Nippon Shokubai Co., Ltd. (JP) | 2006-02-15 | — | — | EP | disclosed |
| US-20060029811-A1 | mixing a phenolic compound containing the inorganic microfine particle(SiO2) and a compound containing at least one of the glycidyl group and/or an epoxy group containing the inorganic microfine particle; fireproofing; good mechanical properties; heat resistance; automobiles, construction, electronics | NIPPON SHOKUBAI CO., LTD. (JP) | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | ALDH1A1 617/4885RAB9A 777/4885NPC1 745/4885 |
| US-20100317774-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | PIEZO1, ORAI2, ARID2 | ALDH1A1 1779/4885RAB9A 3508/4885NPC1 3012/4885 |
| US-20090312326-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | ALDH1A1 617/4885RAB9A 777/4885NPC1 745/4885 |
| US-20130338363-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | ZYX, NOX3, NOXO1 | ALDH1A1 1943/4885RAB9A 3614/4885NPC1 3187/4885 |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | ALDH1A1 617/4885RAB9A 777/4885NPC1 745/4885 |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | ALDH1A1 617/4885RAB9A 777/4885NPC1 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.