Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903020 | 0.95 | SMN1; SMN2 (0.58) | KDM4ESMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL31647674 | 0.75 | ALDH1A1 (0.56) | KDM4ESMN1; SMN2ALDH1A1HSD17B10MAPT | |
| SCHEMBL23793117 | 0.75 | SMN1; SMN2 (0.60) | KDM4ESMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL16019318 | 0.75 | SMN1; SMN2 (0.93) | KDM4ESMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL16019317 | 0.75 | SMN1; SMN2 (0.60) | KDM4ESMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL29375167 | 0.75 | SMN1; SMN2 (0.93) | KDM4ESMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL30471680 | 0.75 | SMN1; SMN2 (0.60) | KDM4ESMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL15116256 | 0.75 | SMN1; SMN2 (0.65) | KDM4ESMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL1101890 | 0.74 | KDM4E (1.00) | KDM4ESMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL23782845 | 0.74 | GAA (0.40) | KDM4ESMN1; SMN2ALDH1A1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970455-B1 | 7-(4-fluorobenzylidene)-4-(4-fluorophenyl)-2-methoxy-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile as an antimicrobial compound | King Faisal University (SA) | 2024-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970455-B1 | 7-(4-fluorobenzylidene)-4-(4-fluorophenyl)-2-methoxy-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile as an antimicrobial compound | CASP4, CASP7, MFN2 | KDM4E 2178/4885SMN1; SMN2 4057/4885ALDH1A1 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.