Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008439 | 0.75 | NOS3 (0.43) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL31303677 | 0.75 | NOS3 (0.43) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL19979167 | 0.70 | SIGMAR1 (0.39) | SIGMAR1CYP19A1CYP11B1CYP11B2CHRNB2 | |
| SCHEMBL16930218 | 0.69 | PNMT (0.41) | — | |
| SCHEMBL14725544 | 0.68 | CYP11B2 (0.38) | SIGMAR1CYP19A1CYP11B1CYP11B2CHRNB2 | |
| SCHEMBL21505568 | 0.67 | SIGMAR1 (0.36) | SIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL14348196 | 0.66 | SIGMAR1 (0.46) | SIGMAR1CYP19A1CYP11B1CYP11B2CHRNB2 | |
| SCHEMBL14490656 | 0.66 | SIGMAR1 (0.46) | SIGMAR1CYP19A1CYP11B1CYP11B2CHRNB2 | |
| SCHEMBL277412 | 0.66 | — | — | |
| SCHEMBL13291916 | 0.66 | SIGMAR1 (0.46) | SIGMAR1CYP19A1CYP11B1CYP11B2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024063576-A1 | NOVEL QUINAZOLINE COMPOUND AS KRAS INHIBITOR | 일동제약(주) | 2024-03-28 | — | — | WO | disclosed |