Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187834 | 1.00 | MCHR1 (0.40) | MCHR1HRH3ADRA2AADRA2BADRA2C | |
| SCHEMBL9928159 | 0.76 | DRD2 (0.53) | HTR2AHTR2CHTR2BHTR1ADRD2 | |
| SCHEMBL29187833 | 0.75 | HRH3 (0.51) | MCHR1HRH3ADRA2AADRA2BADRA2C | |
| SCHEMBL14463791 | 0.70 | HRH3 (0.42) | HRH3HTR2AHTR1ADRD2DRD1 | |
| SCHEMBL10264825 | 0.69 | DRD2 (0.44) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL2741658 | 0.69 | MAOA (0.38) | ADRA2AADRA2BADRA2CHTR2CHTR2B | |
| SCHEMBL31490284 | 0.69 | MCHR1 (0.51) | MCHR1ADRA2AADRA2BADRA2CMEN1 | |
| SCHEMBL14852694 | 0.67 | HTR2C (0.50) | HRH3HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL2625804 | 0.67 | ALOX12 (0.50) | ADRA2AADRA2BADRA2CHTR2CHTR2B | |
| SCHEMBL15395704 | 0.66 | PNMT (0.44) | MCHR1HTR2AHTR2CHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645562-A | Ligand for copper catalytic coupling reaction and application thereof | 江西德璟生物科技有限公司 | 2024-03-05 | — | — | CN | disclosed |