SCHEMBL30828336

SCHEMBL30828336

Cc1ccc(OCC(=O)N(Cc2cccs2)c2ccn[nH]2)cc1C

nearest known ligand 0.81

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 19/20 0.81
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
THRB P10828 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21955512 1.00 TRPM8 (0.81) TRPM8LMNATP53THRB
SCHEMBL2729241 0.90 TRPM8 (1.00) TRPM8
SCHEMBL20640720 0.88 TRPM8 (0.81) TRPM8LMNATP53
SCHEMBL30828335 0.88 TRPM8 (0.81) TRPM8LMNATP53
SCHEMBL20640704 0.88 TRPM8 (1.00) TRPM8LMNATP53THRB
SCHEMBL6398201 0.87 TRPM8 (0.76) TRPM8LMNA
SCHEMBL18706655 0.87 TRPM8 (0.83) TRPM8LMNA
SCHEMBL2730559 0.87 TRPM8 (0.82) TRPM8
SCHEMBL18690998 0.86 TRPM8 (0.81) TRPM8
SCHEMBL18199129 0.84 TRPM8 (0.71) TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025202256-A1 COOLING COMPOSITION FIRMENICH SA (CH) 2025-10-02 WO disclosed
CN-110869365-B Cooling composition 弗门尼舍有限公司 2024-03-29 CN disclosed