Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20640704 | 0.92 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL18706655 | 0.91 | TRPM8 (0.83) | TRPM8 | |
| SCHEMBL2730559 | 0.90 | TRPM8 (0.82) | TRPM8 | |
| SCHEMBL21955512 | 0.90 | TRPM8 (0.81) | TRPM8 | |
| SCHEMBL30828336 | 0.90 | TRPM8 (0.81) | TRPM8 | |
| SCHEMBL20640720 | 0.90 | TRPM8 (0.81) | TRPM8 | |
| SCHEMBL30828335 | 0.90 | TRPM8 (0.81) | TRPM8 | |
| SCHEMBL18690998 | 0.89 | TRPM8 (0.81) | TRPM8 | |
| SCHEMBL6398201 | 0.87 | TRPM8 (0.76) | TRPM8 | |
| SCHEMBL2730239 | 0.86 | TRPM8 (0.75) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355944-B1 | PERFUME EMANATING DEVICE | FIRMENICH & CIE (CH) | 2026-01-07 | — | — | EP | claimed |
| US-20250352444-A1 | Antimicrobial mixtures | SYMRISE AG (DE) | 2025-11-20 | — | — | US | claimed |
| WO-2025202256-A1 | COOLING COMPOSITION | FIRMENICH SA (CH) | 2025-10-02 | — | — | WO | claimed |
| WO-2025132323-A1 | COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT | DSM-FIRMENICH AG (CH) | 2025-06-26 | — | — | WO | claimed |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | SYMRISE AG (DE) | 2025-05-22 | — | — | US | claimed |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | SYMRISE AG (DE) | 2025-02-27 | — | — | US | claimed |
| WO-2025026525-A1 | HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS | SYMRISE AG (DE) | 2025-02-06 | — | — | WO | claimed |
| EP-4469439-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-12-04 | — | — | EP | claimed |
| CN-118984825-A | Novel cooling agent and preparation containing same | 西姆莱斯股份公司 | 2024-11-19 | — | — | CN | claimed |
| EP-4452941-A1 | ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-10-30 | — | — | EP | claimed |
| EP-2931225-B1 | COOLING PREPARATIONS | SYMRISE AG (DE) | 2021-03-31 | — | — | EP | claimed |
| US-20200188289-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | FIRMENICH SA (CH) | 2020-06-18 | — | — | US | claimed |
| EP-3652171-A1 | COOLING COMPOSITION | Firmenich SA (CH) | 2020-05-20 | — | — | EP | claimed |
| EP-3624757-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | Firmenich SA (CH) | 2020-03-25 | — | — | EP | claimed |
| CN-110869365-A | Cooling composition | 弗门尼舍有限公司 | 2020-03-06 | — | — | CN | claimed |
| CN-110621287-A | Composition comprising essential oils | 弗门尼舍有限公司 | 2019-12-27 | — | — | CN | claimed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | claimed |
| WO-2019012071-A1 | COOLING COMPOSITION | FIRMENICH SA (CH) | 2019-01-17 | — | — | WO | claimed |
| WO-2018211420-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | FIRMENICH SA (CH) | 2018-11-22 | — | — | WO | claimed |
| EP-3355944-A1 | PERFUME EMANATING DEVICE | Firmenich SA (CH) | 2018-08-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250352444-A1 | Antimicrobial mixtures | LRBA, MGLL, TAS2R50 | TRPM8 205/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | TRPM8 1/4885 |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | TAS2R5, TAS2R7, TAS2R8 | TRPM8 363/4885 |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | TTR, TAS2R5, TAS2R50 | TRPM8 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.