Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 18/20 | 0.81 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828335 | 1.00 | TRPM8 (0.81) | TRPM8TP53LMNA | |
| SCHEMBL2729241 | 0.90 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL2730559 | 0.89 | TRPM8 (0.82) | TRPM8 | |
| SCHEMBL30828336 | 0.88 | TRPM8 (0.81) | TRPM8TP53LMNA | |
| SCHEMBL21955512 | 0.88 | TRPM8 (0.81) | TRPM8TP53LMNA | |
| SCHEMBL20640704 | 0.86 | TRPM8 (1.00) | TRPM8TP53LMNA | |
| SCHEMBL6398201 | 0.85 | TRPM8 (0.76) | TRPM8LMNA | |
| SCHEMBL18706655 | 0.85 | TRPM8 (0.83) | TRPM8LMNA | |
| SCHEMBL2730239 | 0.85 | TRPM8 (0.75) | TRPM8TP53 | |
| SCHEMBL18690998 | 0.84 | TRPM8 (0.81) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869365-B | Cooling composition | 弗门尼舍有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11174249-B2 | Cooling composition | FIRMENICH SA (CH) | 2021-11-16 | — | — | US | disclosed |
| EP-3652171-B1 | COOLING COMPOSITIONS CONTAINING AN AMIDE AND AN ALKYL LACTATE | FIRMENICH & CIE (CH) | 2021-09-08 | — | — | EP | disclosed |
| US-20200157083-A1 | COOLING COMPOSITION | FIRMENICH SA (CH) | 2020-05-21 | — | — | US | disclosed |
| EP-3652171-A1 | COOLING COMPOSITION | Firmenich SA (CH) | 2020-05-20 | — | — | EP | disclosed |
| CN-110869365-A | Cooling composition | 弗门尼舍有限公司 | 2020-03-06 | — | — | CN | disclosed |
| WO-2019012071-A1 | COOLING COMPOSITION | FIRMENICH SA (CH) | 2019-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157083-A1 | COOLING COMPOSITION | LDHA, LDHB, ADH1A | TRPM8 1016/4885TP53 1460/4885LMNA 338/4885 |
| US-11174249-B2 | Cooling composition | LDHA, LDHB, ADH1A | TRPM8 1016/4885TP53 1460/4885LMNA 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.