Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | GFER | P55789 | 3/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.78 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.78 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | UQCRB | P14927 | 2/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280452 | 0.92 | LMNA (0.68) | ALDH1A1MAPTTDP1LMNAGFER | |
| SCHEMBL14018736 | 0.92 | ALDH1A1 (0.91) | ALDH1A1MAPTTDP1LMNAGFER | |
| SCHEMBL8279538 | 0.88 | ALDH1A1 (0.62) | ALDH1A1MAPTTDP1LMNAGFER | |
| SCHEMBL2832955 | 0.86 | MAPT (0.73) | ALDH1A1MAPTTDP1LMNAGFER | |
| SCHEMBL28032113 | 0.86 | ALDH1A1 (0.73) | ALDH1A1MAPTTDP1LMNAGFER | |
| SCHEMBL5718766 | 0.86 | ALDH1A1 (0.73) | ALDH1A1MAPTTDP1LMNAGFER | |
| SCHEMBL8752441 | 0.83 | ALDH1A1 (0.72) | ALDH1A1MAPTTDP1LMNAGFER | |
| SCHEMBL13987950 | 0.81 | HDAC3 (0.70) | — | |
| SCHEMBL4883342 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPTTDP1LMNAGFER | |
| SCHEMBL15482206 | 0.80 | HDAC6 (0.68) | ALDH1A1MAPTTDP1LMNAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | SAINT LOUIS UNIVERSITY (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | ABCC1, ARG1, SLC11A2 | ALDH1A1 2841/4885MAPT 3344/4885TDP1 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.