Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | UQCRB | P14927 | 3/20 | 0.68 |
| ▸ | GFER | P55789 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828575 | 0.92 | ALDH1A1 (0.78) | LMNAMAPTALDH1A1TDP1UQCRB | |
| SCHEMBL21086838 | 0.87 | UQCRB (0.86) | LMNAMAPTALDH1A1UQCRBGFER | |
| SCHEMBL14018736 | 0.85 | ALDH1A1 (0.91) | LMNAMAPTALDH1A1TDP1GFER | |
| SCHEMBL1592323 | 0.82 | UQCRB (0.76) | LMNAMAPTALDH1A1UQCRBGFER | |
| SCHEMBL8279538 | 0.81 | ALDH1A1 (0.62) | LMNAMAPTALDH1A1TDP1GFER | |
| SCHEMBL6296969 | 0.81 | UQCRB (1.00) | LMNAMAPTALDH1A1UQCRBGFER | |
| SCHEMBL2832955 | 0.80 | MAPT (0.73) | LMNAMAPTALDH1A1TDP1GFER | |
| SCHEMBL5718766 | 0.79 | ALDH1A1 (0.73) | LMNAMAPTALDH1A1TDP1GFER | |
| SCHEMBL28032113 | 0.79 | ALDH1A1 (0.73) | LMNAMAPTALDH1A1TDP1GFER | |
| SCHEMBL930602 | 0.77 | MAPT (0.82) | LMNAMAPTALDH1A1TDP1UQCRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |