Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985042 | 1.00 | ALDH1A1 (0.57) | ALDH1A1RXFP1KDM4EHTTMAPT | |
| SCHEMBL24714302 | 0.71 | ALDH1A1 (0.68) | ALDH1A1RXFP1KDM4EHTTMAPT | |
| SCHEMBL8941729 | 0.70 | XDH (0.54) | KDM4EMAPTLMNAKMT2AMEN1 | |
| SCHEMBL29390286 | 0.70 | XDH (0.54) | KDM4EMAPTLMNAKMT2AMEN1 | |
| SCHEMBL11006722 | 0.68 | CYP3A4 (0.54) | ALDH1A1KDM4EHTTMAPTSMN1; SMN2 | |
| SCHEMBL733998 | 0.67 | EPHX1 (0.55) | ALDH1A1KDM4EHTTMAPTSMN1; SMN2 | |
| SCHEMBL19707725 | 0.67 | MAPT (0.76) | ALDH1A1KDM4EHTTMAPTSMN1; SMN2 | |
| SCHEMBL4072785 | 0.66 | L3MBTL1 (0.57) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL28877123 | 0.66 | CYP3A4 (0.60) | ALDH1A1KDM4EHTTMAPTSMN1; SMN2 | |
| SCHEMBL11432298 | 0.64 | CA2 (0.56) | ALDH1A1KDM4EHTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250366472-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2025-12-04 | — | — | US | disclosed |
| EP-4551018-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | Royal Holloway & Bedford New College (GB) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024009078-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2024-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250366472-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | DAO, ACOX1, HAO1 | ALDH1A1 179/4885RXFP1 1977/4885KDM4E 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.