Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265468 | 0.88 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL166586 | 0.86 | GABRA1 (0.52) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL5226691 | 0.86 | ALDH1A1 (0.57) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL8791921 | 0.86 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL9777521 | 0.82 | GABRA1 (0.40) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL8219343 | 0.77 | GABRA1 (0.55) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL4456728 | 0.76 | GABRA1 (0.54) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL590015 | 0.76 | MEN1 (0.50) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL5824091 | 0.75 | GABRA1 (0.58) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL2141001 | 0.75 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7777073-B2 | Topical delivery system for antiaging and skin whitening agents | BIODERM RESEARCH (US) | 2010-08-17 | — | — | US | disclosed |
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | BIODERM RESEARCH (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | TYR, MMP17, MMP1 | GABRA1 4083/4885GABRB2 3279/4885ALDH1A1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.