Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 3/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | PER2 | O15055 | 5/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21314781 | 1.00 | RAPGEF3 (0.39) | RAPGEF3RAPGEF4PARP1HDAC1HDAC8 | |
| SCHEMBL31479640 | 0.81 | PER2 (0.43) | RAPGEF3RAPGEF4PARP1PER2CRY2 | |
| SCHEMBL21314738 | 0.78 | HDAC1 (0.38) | HDAC1HDAC8HDAC6HDAC5PER2 | |
| SCHEMBL21314741 | 0.78 | HDAC1 (0.38) | HDAC1HDAC8HDAC6HDAC5PER2 | |
| SCHEMBL30832925 | 0.78 | HDAC1 (0.38) | HDAC1HDAC8HDAC6HDAC5PER2 | |
| SCHEMBL16480455 | 0.77 | PARP1 (0.41) | PARP1HDAC1HDAC8HDAC6NOTUM | |
| SCHEMBL16480402 | 0.74 | PARP1 (0.46) | PARP1PER2CRY2NOTUMNPC1 | |
| SCHEMBL21314780 | 0.74 | KDM1A (0.40) | KDM1AKCNH2KDM1B | |
| SCHEMBL30832883 | 0.74 | KDM1A (0.40) | KDM1AKCNH2KDM1B | |
| SCHEMBL21314771 | 0.72 | HDAC1 (0.36) | HDAC1HDAC8HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868052-B | Phenyl pyrrolidone formyl peptide 2 receptor agonist | 百时美施贵宝公司 | 2024-03-08 | — | — | CN | disclosed |