SCHEMBL30832883

SCHEMBL30832883

CC1CC(N)C(=O)N1c1ccc(Br)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.40
KCNH2 Q12809 2/20 0.40
KDM1B Q8NB78 2/20 0.40
AADAT Q8N5Z0 1/20 0.32
FPR1 P21462 4/20 0.31
FPR2 P25090 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21314780 1.00 KDM1A (0.40) KDM1AKCNH2KDM1BAADATFPR1
SCHEMBL21314730 0.77 FPR1 (0.42) FPR1FPR2
SCHEMBL21314744 0.77
SCHEMBL21314762 0.74 DUT (0.32) KDM1AKCNH2KDM1B
SCHEMBL30832909 0.74 RAPGEF3 (0.39) KDM1AKCNH2KDM1B
SCHEMBL21314781 0.74 RAPGEF3 (0.39) KDM1AKCNH2KDM1B
Hydrochloric Acid SCHEMBL30832920 0.72 FPR2 (0.56) FPR1FPR2
Hydrochloric Acid SCHEMBL21314763 0.72 FPR2 (0.56) FPR1FPR2
SCHEMBL21341184 0.71 FPR1 (0.41) KDM1AFPR1FPR2
SCHEMBL30832910 0.71 FPR1 (0.41) KDM1AFPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111868052-B Phenyl pyrrolidone formyl peptide 2 receptor agonist 百时美施贵宝公司 2024-03-08 CN disclosed