Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833145 | 0.88 | CKS1B (0.42) | CKS1BSKP1SKP2TBK1SMARCA2 | |
| SCHEMBL30833122 | 0.75 | MAPT (0.47) | MAPTSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL2366192 | 0.72 | MEN1 (0.55) | CKS1BSKP1SKP2MAPTPOLB | |
| SCHEMBL31727494 | 0.71 | NR1H2 (0.43) | CKS1BSKP1SKP2MAPTSMARCA2 | |
| SCHEMBL21159159 | 0.71 | GPR119 (0.60) | CKS1BSKP1SKP2MAPTPOLB | |
| SCHEMBL30899649 | 0.71 | GRM1 (0.49) | CDK9 | |
| SCHEMBL30366133 | 0.71 | GRM1 (0.49) | CDK9 | |
| SCHEMBL1833105 | 0.71 | MTOR (0.41) | TBK1MAPTSMN1; SMN2USP2 | |
| SCHEMBL21871400 | 0.70 | PDK4 (0.52) | SMN1; SMN2USP2GPR119 | |
| SCHEMBL31583898 | 0.70 | GRM1 (0.55) | CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587432-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | Cerevel Therapeutics, LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059249-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |