Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833102 | 0.88 | CKS1B (0.42) | CKS1BSKP1SKP2GPR119TBK1 | |
| SCHEMBL31378528 | 0.76 | GPR119 (0.49) | CKS1BSKP1SKP2GPR119SMARCA2 | |
| SCHEMBL30833113 | 0.76 | PIK3CA (0.49) | CKS1BSKP1SKP2GPR119SMARCA2 | |
| SCHEMBL26113732 | 0.75 | POLB (0.49) | CKS1BSKP1SKP2GPR119SMARCA2 | |
| SCHEMBL30833118 | 0.75 | GPR119 (0.48) | CKS1BSKP1SKP2GPR119SMARCA2 | |
| SCHEMBL30515311 | 0.75 | TBK1 (0.43) | CKS1BSKP1SKP2GPR119TBK1 | |
| SCHEMBL31651742 | 0.74 | GPR119 (0.47) | CKS1BSKP1SKP2GPR119SMARCA2 | |
| SCHEMBL30833112 | 0.74 | PIK3CA (0.48) | CKS1BSKP1SKP2GPR119SMARCA2 | |
| SCHEMBL24989545 | 0.73 | GPR119 (0.47) | CKS1BSKP1SKP2GPR119SMARCA2 | |
| SCHEMBL22328950 | 0.72 | GRM1 (0.57) | GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098026-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS LLC (US) | 2026-04-09 | — | — | US | disclosed |
| EP-4587432-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | Cerevel Therapeutics, LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059249-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260098026-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CHRM1, CHRM2, CHRM4 | CKS1B 922/4885SKP1 799/4885SKP2 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.