Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899639 | 0.78 | MEN1 (0.49) | MAPTLMNASMN1; SMN2USP2TP53 | |
| SCHEMBL30366127 | 0.78 | MEN1 (0.49) | MAPTLMNASMN1; SMN2USP2TP53 | |
| SCHEMBL2681920 | 0.77 | MEN1 (0.48) | MAPTLMNASMN1; SMN2USP2TP53 | |
| SCHEMBL12211468 | 0.77 | MEN1 (0.48) | MAPTLMNASMN1; SMN2USP2TP53 | |
| SCHEMBL30833111 | 0.75 | HRH4 (0.43) | — | |
| SCHEMBL30833102 | 0.75 | CKS1B (0.42) | MAPTSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL31727686 | 0.74 | MAPT (0.44) | MAPTLMNAMEN1KMT2AGPR119 | |
| SCHEMBL2366192 | 0.74 | MEN1 (0.55) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20574020 | 0.73 | RECQL (0.43) | RECQLSMN1; SMN2USP2GPR119 | |
| SCHEMBL21159159 | 0.73 | GPR119 (0.60) | MAPTLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587432-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | Cerevel Therapeutics, LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059249-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |