Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 19/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 18/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201384 | 0.72 | MEN1 (0.57) | OPRK1 | |
| SCHEMBL28496122 | 0.70 | SIRT1 (0.45) | — | |
| SCHEMBL3687747 | 0.68 | MAPKAPK2 (0.52) | — | |
| SCHEMBL30833217 | 0.67 | OPRK1 (0.53) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833197 | 0.66 | KCNH2 (0.56) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL5454077 | 0.66 | CDC42 (0.58) | OPRM1 | |
| SCHEMBL30833216 | 0.65 | KCNH2 (0.58) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833214 | 0.64 | OPRK1 (0.59) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833204 | 0.64 | KCNH2 (0.56) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30571064 | 0.63 | MAPT (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |