Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27171378 | 0.81 | ACHE (0.41) | ACHEPARP1MAPTCHUKCHEK1 | |
| SCHEMBL27171320 | 0.78 | CHUK (0.47) | ACHEPARP1CHUKKDM4EALDH1A1 | |
| SCHEMBL27171376 | 0.72 | MAPT (0.41) | ACHEMAPTHTR6KDM4EALDH1A1 | |
| SCHEMBL27171383 | 0.72 | CHEK1 (0.40) | ACHEMAPTCHEK1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3522469 | 0.71 | RAB9A (0.53) | ACHEMAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL27171375 | 0.71 | MAPT (0.49) | ACHEPARP1MAPTCHUKKDM4E | |
| SCHEMBL30766229 | 0.70 | ACHE (0.42) | ACHEPARP1MAPTCHUKCHEK1 | |
| SCHEMBL5371096 | 0.70 | PDPK1 (0.42) | ALDH1A1LMNACYP1A2POLBCYP3A4 | |
| SCHEMBL27171380 | 0.69 | KMT2A (0.45) | ACHEMAPTCHUKKDM4EMEN1 | |
| SCHEMBL27171390 | 0.69 | NFKB1 (0.37) | ALDH1A1TP53GAANFKB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11945820-B1 | Pyrrolo[3,2-c][2,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | King Faisal University (SA) | 2024-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11945820-B1 | Pyrrolo[3,2-c][2,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | CSNK2A2, CSNK2A3, CKS2 | ACHE 1240/4885PARP1 1321/4885MAPT 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.