Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30201490 | 0.87 | ARG1 (0.35) | JAK2JAK1TYK2JAK3HRH3 | |
| SCHEMBL4851359 | 0.73 | OPRM1 (0.52) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL30833237 | 0.69 | OPRM1 (0.31) | OPRK1KCNH2OPRM1 | |
| SCHEMBL15021133 | 0.68 | CHRM2 (0.58) | HRH3OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL21777244 | 0.68 | CHRM2 (0.58) | HRH3OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL168287 | 0.68 | CHRM2 (0.58) | HRH3OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL21772974 | 0.68 | CHRM2 (0.58) | HRH3OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL168286 | 0.68 | CHRM2 (0.58) | HRH3OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL30833221 | 0.68 | PTPN11 (0.40) | — | |
| SCHEMBL3881484 | 0.67 | DRD2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |