Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 4/20 | 0.35 |
| ▸ | ARG2 | P78540 | 4/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833230 | 0.87 | JAK2 (0.41) | JAK1JAK2TYK2JAK3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL30201414 | 0.80 | OPRM1 (0.51) | KCNH2OPRK1OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL30201435 | 0.79 | LTA4H (0.49) | ARG1ARG2KCNH2OPRK1OPRM1 | |
| Trifluoroacetic Acid SCHEMBL30201373 | 0.76 | ARG1 (0.38) | ARG1ARG2KCNH2OPRK1HRH3 | |
| Trifluoroacetic Acid SCHEMBL30201424 | 0.76 | OPRM1 (0.52) | KCNH2OPRK1OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL30201500 | 0.76 | CYP3A4 (0.39) | ARG1ARG2JAK1JAK2TYK2 | |
| Trifluoroacetic Acid SCHEMBL30201381 | 0.75 | KCNH2 (0.53) | ARG1ARG2KCNH2OPRK1OPRM1 | |
| Trifluoroacetic Acid SCHEMBL31622406 | 0.75 | ARG1 (0.37) | ARG1ARG2KCNH2OPRK1HRH3 | |
| Trifluoroacetic Acid SCHEMBL30201583 | 0.75 | LTA4H (0.48) | ARG1ARG2KCNH2OPRK1OPRM1 | |
| Trifluoroacetic Acid SCHEMBL30201455 | 0.75 | ARG1 (0.54) | ARG1ARG2KCNH2OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |