Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833280 | 0.78 | PDE3B (0.44) | CYP3A4LMNAMAPTCRBNCYP11B1 | |
| SCHEMBL24677008 | 0.78 | PDE3B (0.44) | CYP3A4LMNAMAPTCRBNCYP11B1 | |
| SCHEMBL29769797 | 0.74 | CD38 (0.35) | EGLN2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30833285 | 0.73 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL30833279 | 0.72 | OPRK1 (0.35) | LMNAGAACYP11B1CYP11B2 | |
| SCHEMBL2629369 | 0.63 | CYP3A4 (0.42) | EGLN2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL24713314 | 0.62 | LOXL2 (0.44) | EGLN2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9521235 | 0.61 | CYP3A4 (0.58) | EGLN2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL25144382 | 0.61 | LOXL2 (0.43) | EGLN2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29495177 | 0.61 | CYP1A2 (0.47) | EGLN2CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580829-A | Quinoline and azaquinolines as inhibitors of CD38 | 勃林格英格翰国际有限公司 | 2024-02-20 | — | — | CN | disclosed |