Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125026 | 0.72 | CYP11B2 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL31125023 | 0.72 | CYP11B2 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL30833286 | 0.72 | EGLN2 (0.39) | LMNAGAACYP11B1CYP11B2 | |
| SCHEMBL18227002 | 0.70 | CYP11B2 (0.48) | GABRA1GABRG2GABRB3GABRA5CYP11B1 | |
| SCHEMBL21663004 | 0.67 | SMN1; SMN2 (0.34) | OPRK1PDE4DLMNAGAATSPO | |
| SCHEMBL30099722 | 0.67 | GABRA1 (0.48) | OPRK1PDE4DLMNAGAATSPO | |
| SCHEMBL30833278 | 0.67 | CASP3 (0.57) | OPRK1PDE4DLMNAGAATSPO | |
| SCHEMBL8054672 | 0.65 | TTR (0.52) | OPRK1PDE4DLMNAGABRA1GABRG2 | |
| SCHEMBL27408527 | 0.63 | CHRNB2 (0.31) | — | |
| SCHEMBL22583158 | 0.62 | MEN1 (0.40) | PDE4DGAAMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580829-A | Quinoline and azaquinolines as inhibitors of CD38 | 勃林格英格翰国际有限公司 | 2024-02-20 | — | — | CN | disclosed |