Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333390 | 0.87 | ALDH1A1 (0.44) | KMT2AHSD17B2MEN1ALDH1A1HSD17B1 | |
| SCHEMBL30833317 | 0.81 | MAPT (0.37) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30847838 | 0.78 | ALOX15 (0.45) | MAPTKDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28000518 | 0.76 | ALDH1A1 (0.58) | MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL26473308 | 0.72 | RXRA (0.50) | MAPTKDM4ELMNA | |
| SCHEMBL9956630 | 0.71 | HSD17B2 (0.60) | HSD17B2HSD17B1 | |
| SCHEMBL15864862 | 0.71 | ALDH1A1 (0.46) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18612985 | 0.71 | ALDH1A1 (0.49) | NPC1SMN1; SMN2KMT2AHSD17B2MEN1 | |
| SCHEMBL29460229 | 0.71 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2KMT2AHSD17B2 | |
| SCHEMBL11854125 | 0.70 | ALDH1A1 (0.51) | MAPTNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736206-A | Urea derivatives as MC4R antagonists, pharmaceutical compositions and pharmaceutical applications thereof | 长春金赛药业有限责任公司 | 2024-03-22 | — | — | CN | disclosed |