Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18593560 | 0.89 | TSPO (0.48) | ALDH1A1HTTKMT2AMEN1TSHR | |
| SCHEMBL29460229 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HTTKMT2AMEN1TSHR | |
| SCHEMBL5333390 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1TSHRPOLB | |
| SCHEMBL31034446 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2APOLBHSD17B2HSD17B1 | |
| SCHEMBL11027897 | 0.81 | HSD17B2 (0.61) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL17460819 | 0.80 | HSP90AA1 (0.50) | ALDH1A1HTTKMT2AMEN1TSHR | |
| SCHEMBL2537515 | 0.79 | ALDH1A1 (0.71) | ALDH1A1HTTKMT2APOLBSMN1; SMN2 | |
| SCHEMBL16665268 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1TSHRPOLB | |
| SCHEMBL3122515 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTKMT2AMEN1TSHR | |
| SCHEMBL18612984 | 0.76 | LMNA (0.50) | ALDH1A1HTTTSHRPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057943-B1 | PYRIMIDINE FGFR4 INHIBITORS | EISAI R&D MAN CO LTD (JP) | 2018-04-25 | — | — | EP | disclosed |
| US-20170067168-A1 | PORPHYRIN MOLECULAR CATALYSTS FOR SELECTIVE ELECTROCHEMICAL REDUCTION OF CO2 INTO CO | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170067168-A1 | PORPHYRIN MOLECULAR CATALYSTS FOR SELECTIVE ELECTROCHEMICAL REDUCTION OF CO2 INTO CO | CYC1, MT-CO2, MT-CO1 | ALDH1A1 3714/4885HTT 2347/4885KMT2A 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.